Arabinosyltransferase
From Infogalactic: the planetary knowledge core
| Arabinosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Arabinose_trans | ||||||||
| Pfam | PF04602 | ||||||||
| Pfam clan | CL0111 | ||||||||
| InterPro | IPR007680 | ||||||||
| CAZy | GT53 | ||||||||
|
|||||||||
In molecular biology, an arabinosyltransferase is a transferase enzyme acting upon arabinose.[1] This enzyme is involved in polymerisation of arabinogalactan (an essential component of the mycobacterial cell wall). Mycobacterially, the more precise term is arabinofuranosyltransferase, since the arabinose residues occur only in a furanose form.
This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.[2]
References
- ↑ "Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors." US National Library. Retrieved 2014-3-11.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
This article incorporates text from the public domain Pfam and InterPro IPR007680
