Cannabidivarin

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Cannabidivarin
Cannabidivarin.svg
Cannabidivarin molecule ball.png
Systematic (IUPAC) name
2-((1S,6S)-3-methyl-6-(prop-1-en-2-yl)
cyclohex-2-enyl)-5-propylbenzene-1,3-diol
Identifiers
CAS Number 24274-48-4 N
ATC code none
DrugBank none N
ChemSpider 21106275 YesY
Chemical data
Formula C19H26O2
Molecular mass 286.41 g/mol
  • C=C(C)[C@H]2CCC(\C)=C/[C@@H]2c1c(O)cc(CCC)cc1O
  • InChI=1S/C19H26O2/c1-5-6-14-10-17(20)19(18(21)11-14)16-9-13(4)7-8-15(16)12(2)3/h9-11,15-16,20-21H,2,5-8H2,1,3-4H3/t15-,16+/m1/s1 YesY
  • Key:REOZWEGFPHTFEI-CVEARBPZSA-N YesY
 NYesY (what is this?)  (verify)

Cannabidivarin (CBDV) is a non-psychoactive cannabinoid found in Cannabis. It is a homolog of cannabidiol (CBD), with the side-chain shortened by two methylene bridges (CH2 units). Plants with relatively high levels of CBDV have been reported in feral populations of C. indica ( = C. sativa ssp. indica var. kafiristanica) from northwest India, and in hashish from Nepal.[1][2] CBDV has anticonvulsant effects.[3]

Similarly to CBD, it has 7 double bond isomers and 30 stereoisomers (see: Cannabidiol#Double bond isomers and their stereoisomers). It is not scheduled by Convention on Psychotropic Substances. It is being actively developed by GW Pharmaceuticals[4] (as GWP42006)because of a demonstrated neurochemical pathway for previously-observed anti-epileptic and anti-convulsive action.[5] GW has begun a phase 2 trial for adult epilepsy,[6] and is to begin trials of this CBDV product in children in 2016 in Australia.[7][8]

See also

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ http://www.gwpharm.com/therapeutic-areas.aspx[full citation needed]
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  6. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  7. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  8. ↑ Lua error in package.lua at line 80: module 'strict' not found.


External links

  • Erowid Compounds found in Cannabis sativa


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