Ethacridine lactate
From Infogalactic: the planetary knowledge core
Skeletal formulas of ethacridine lactate | |
Ball-and-stick models of the component ions of ethacridine lactate | |
Systematic (IUPAC) name | |
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7-ethoxyacridine-3,9-diamine; 2-hydroxypropanoic acid
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Clinical data | |
AHFS/Drugs.com | International Drug Names |
Identifiers | |
CAS Number | 1837-57-6 |
ATC code | B05CA08 (WHO) D08AA01 |
PubChem | CID: 15789 |
ChemSpider | 15012 |
KEGG | D01248 |
ChEMBL | CHEMBL582355 |
Chemical data | |
Formula | C18H21N3O4 |
Molecular mass | 343.37 |
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Ethacridine lactate (ethacridine monolactate monohydrate, acrinol, trade name Rivanol) is an aromatic organic compound based on acridine. Its formal name is 2-ethoxy-6,9-diaminoacridine monolactate monohydrate. It forms orange-yellow crystals with a melting point of 226 °C and it has a stinging smell.
Its primary use is as an antiseptic in solutions of 0.1%.
Ethacridine is also used as an agent for second trimester abortion. Up to 150 ml of a 0.1% solution is instilled extra-amniotically using a foley catheter. After 20 to 40 hours, 'mini labor' ensues. In China, an intra-amniotic method has also been used. Ethacridine as an abortifacient is found to be safer and better tolerated than 20% hypertonic saline.
References
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- Merck Index, 11th Ed., 3668.
Categories:
- Pages with broken file links
- Chemical articles having calculated molecular weight overwritten
- Infobox drug articles without a structure image
- Chemical pages without DrugBank identifier
- Articles without UNII source
- Drugs with no legal status
- Antiseptics
- Aromatic compounds
- Lactates
- Acridines
- Phenol ethers
- Aromatic amines