GW-842,166X

GW-842,166X
	200px
Systematic (IUPAC) name
	2-(2,4-dichloroanilino)-N-(tetrahydropyran-4-ylmethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide
Identifiers
CAS Number	666260-75-9
PubChem	CID: 10253143
ChemSpider	8428629
ChEMBL	CHEMBL225411
Chemical data
Formula	C18H17Cl2F3N4O2
Molecular mass	449.254 g/mol
	SMILES C3COCCC3CNC(=O)c1cnc(nc1C(F)(F)F)Nc2ccc(Cl)cc2Cl ;
	InChI InChI=1S/C18H17Cl2F3N4O2/c19-11-1-2-14(13(20)7-11)26-17-25-9-12(15(27-17)18(21,22)23)16(28)24-8-10-3-5-29-6-4-10/h1-2,7,9-10H,3-6,8H2,(H,24,28)(H,25,26,27) ; Key:TWQYWUXBZHPIIV-UHFFFAOYSA-N ;
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GW-842,166X is a drug which acts as a potent and selective cannabinoid CB₂ receptor agonist, with a novel chemical structure based on a pyrimidine core. It has potent analgesic, anti-inflammatory and anti-hyperalgesic actions in animal models, but without cannabis-like behavioural effects due to its extremely low affinity for the CB₁ receptor.^[1]^[2]^[3]

References

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