Trifunctional purine biosynthetic protein adenosine-3

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Trifunctional purine biosynthetic protein adenosine-3 is an enzyme that in humans is encoded by the GART gene.[1]

This protein is a trifunctional polypeptide. It has Phosphoribosylamine—glycine ligase (EC 6.3.4.13), Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2), AIR synthetase (FGAM cyclase) (EC 6.3.3.1) activity which is required for de novo purine biosynthesis.

References

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Further reading

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External links


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