Gram-negative bacterial infection
From Infogalactic: the planetary knowledge core
Gram-negative bacterial infection | |
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Gram negative cell wall
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Classification and external resources | |
Specialty | Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value). |
Patient UK | Gram-negative bacterial infection |
MeSH | D016905 |
Gram-negative bacterial infection refers to a disease caused by gram-negative bacteria. One example is E. coli.[1]
It is important to recognize that this class is defined morphologically (by the presence of a bacterial outer membrane), and not histologically (by a pink appearance when stained), though the two usually coincide.
One reason for this division is that the outer membrane is of major clinical significance: it can play a role in the reduced effectiveness of certain antibiotics,[2] and it is the source of endotoxin.[3]
The gram status of some organisms is complex or disputed:
- Mycoplasma are sometimes considered gram negative,[4][5] but because of its lack of a cell wall and unusual membrane composition, it is sometimes considered separately from other gram-negative bacteria.[6]
- Gardnerella is often considered gram negative,[7] but it is classified in MeSH as both gram positive and gram negative.[8] It has some traits of gram positive bacteria,[9] but has a gram negative appearance.[10] It has been described as a "gram-variable rod".[11][12]
References
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- ↑ Lua error in package.lua at line 80: module 'strict' not found.
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- ↑ Mycoplasma at the US National Library of Medicine Medical Subject Headings (MeSH)
- ↑ "mycoplasma" at Dorland's Medical Dictionary
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ "Gardnerella" at Dorland's Medical Dictionary
- ↑ Gardnerella at the US National Library of Medicine Medical Subject Headings (MeSH)
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