JWH-251

JWH-251

Names
IUPAC name 2-(2-methylphenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone
Identifiers
CAS Number	864445-39-6 N
ChEMBL	ChEMBL364820 Y
ChemSpider	9791472 Y
Jmol 3D model	Interactive image
PubChem	11616723
InChI InChI=1S/C22H25NO/c1-3-4-9-14-23-16-20(19-12-7-8-13-21(19)23)22(24)15-18-11-6-5-10-17(18)2/h5-8,10-13,16H,3-4,9,14-15H2,1-2H3 Y Key: YBIPNGRKUAVSBG-UHFFFAOYSA-N Y
SMILES O=C(c2c1ccccc1n(c2)CCCCC)Cc3ccccc3C
Properties
Chemical formula	C22H25NO
Molar mass	319.440 g/mol
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

JWH-251 (1-pentyl-3-(2-methylphenylacetyl)indole) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about 5x selectivity for CB₁ with a K_i of 29nM and 146nM at CB₂. Similar to the related 2'-methoxy compound JWH-250, the 2'-chloro compound JWH-203, and the 2'-bromo compound JWH-249, JWH-251 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds.