JWH-302

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JWH-302
JWH-302 structure.png
Systematic (IUPAC) name
2-(3-methoxyphenyl)-1-(1-pentylindol-3-yl)ethanone
Identifiers
CAS Number 864445-45-4 N
PubChem CID: 11493740
ChemSpider 9668546 YesY
ChEMBL CHEMBL186674 YesY
Chemical data
Formula C22H25NO2
Molecular mass 335.439 g/mol
  • c2ccc(OC)cc2CC(=O)c(cn1CCCCC)c3ccccc13
  • InChI=1S/C22H25NO2/c1-3-4-7-13-23-16-20(19-11-5-6-12-21(19)23)22(24)15-17-9-8-10-18(14-17)25-2/h5-6,8-12,14,16H,3-4,7,13,15H2,1-2H3 YesY
  • Key:XZVYWLVYUAQEIM-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

JWH-302 or (1-pentyl-3-(3-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family, which acts as a cannabinoid agonist with moderate affinity at both the CB1 and CB2 receptors. It is a positional isomer of the more common drug JWH-250, though it is slightly less potent with a Ki of 17nM at CB1, compared to 11nM for JWH-250.[1][2] Because of their identical molecular weight and similar fragmentation patterns, JWH-302 and JWH-250 can be very difficult to distinguish by GC-MS testing.[3]

References

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  2. Lua error in package.lua at line 80: module 'strict' not found.
  3. 'Herbal High' synthetic Cannabinoid composition, released by ESR July 2011


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