mdx mouse
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The mdx mouse is a popular model for studying Duchenne muscular dystrophy (DMD).
The mdx mouse has a point mutation in its DMD gene, changing the amino acid coding for a glutamine to a threonine. This causes the muscle cells to produce a small, nonfunctional dystrophin protein.[1] As a result, the mouse has a mild form of DMD where there increased muscle damage and weakness.
References
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