PF-3845

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PF-3845
PF-3845 structure.png
Systematic (IUPAC) name
N-3-pyridinyl-4-([3-([5-(trifluoromethyl)-2-pyridinyl]oxy)phenyl]methyl)-1-piperidinecarboxamide
Clinical data
Legal status
Identifiers
CAS Number 1196109-52-0
ATC code None
PubChem CID: 25154867
Chemical data
Formula C24H23F3N4O2
Molecular mass 456.459 g/mol
  • O=C(NC1=CN=CC=C1)N(CC2)CCC2CC3=CC=CC(OC4=NC=C(C(F)(F)F)C=C4)=C3

PF-3845 is a selective inhibitor of fatty acid amide hydrolase.[1] It results in increased levels of anandamide and results in cannabinoid receptor-based effects. It has anti-inflammatory action in mice colitis models. Antidiarrheal and antinociceptive effects were also seen in mouse models of pain.[2]

References

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