Phosalone

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Phosalone
Phosalone.png
Phosalone-spacefilling-from-AHRLS-2011.png
Names
IUPAC name
6-chloro-3-(diethoxyphosphinothioylsulfanylmethyl)-1,3-benzoxazol-2-one
Other names
Zolone
Identifiers
2310-17-0 YesY
ChEBI CHEBI:8121 YesY
ChEMBL ChEMBL1528531 N
ChemSpider 4629 YesY
Jmol 3D model Interactive image
KEGG C11028 YesY
PubChem 4793
UNII 448B85HT8M YesY
  • InChI=1S/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 YesY
    Key: IOUNQDKNJZEDEP-UHFFFAOYSA-N YesY
  • InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3
    Key: IOUNQDKNJZEDEP-UHFFFAOYAA
  • Clc2ccc1c(OC(=O)N1CSP(=S)(OCC)OCC)c2
Properties
C12H15ClNO4PS2
Molar mass 367.80 g·mol−1
Appearance Colorless crystaline
Odor garlic
Density 1.39 g cm−3
Melting point 47.5 to 48 °C (117.5 to 118.4 °F; 320.6 to 321.1 K)
3.05 mg/L
Solubility many organic solvents
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide. It is developed by Rhône-Poulenc in France but EU eliminated it from pesticide registration on December 2006.

The median lethal dose of oral exposure in rat is 85 mg/kg and that of dermal is 390 mg/kg.[1]。It is a weak acetylcholinesterase inhibitor.[2] It is taken by not only oral and inhalation but skin and it causes toxic symptoms peculiar to organophosphorus compounds such as miosis, hypersalivation, hyperhidrosis, chest pressure, pulmonary edema and fecal incontinence.[3] It is flammable and decomposes to toxic gases such as phosphorus oxides, sulfur oxides and nitrogen oxides.[2] It is harmful especially to water creatures.

References

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