RJR-2429

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RJR-2429
RJR-2429 structure.png
Systematic (IUPAC) name
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane
Identifiers
CAS Number 91556-75-1
PubChem CID: 10176454
Chemical data
Formula C12H16N2
Molecular mass 188.27 g/mol
  • C1(C2N(CC3)CCC3C2)=CN=CC=C1

RJR-2429 is a drug that acts as an agonist at neural nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. RJR-2429 is stronger than nicotine but weaker than epibatidine in most assays, and with high affinity for both α3β4 and α4β2 subtypes, as well as the less studied α1βγδ subtype.[1][2][3]

References

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