Romifidine

Romifidine

Systematic (IUPAC) name
N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	Veterinary Use
Routes of administration	IV
Identifiers
CAS Number	65896-16-4 Y
ATCvet code	QN05CM93 (WHO)
PubChem	CID: 71969
ChemSpider	64975 N
UNII	876351L05K Y
Chemical data
Formula	C9H9BrFN3
Molecular mass	258.09
SMILES C1CN=C(N1)NC2=C(C=CC=C2Br)F
InChI InChI=1S/C9H9BrFN3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14) N Key:KDPNLRQZHDJRFU-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Romifidine is a drug that is used in veterinary medicine as a sedative mainly in large animals such as horses, although it may be used in a wide variety of species. It is not used in humans, but is closely related in structure to the commonly used drug clonidine.

Romifidine acts as an agonist at the α₂ adrenergic receptor subtype. Side effects can include bradycardia and respiratory depression. It is often used alongside other sedative or analgesic drugs such as ketamine or butorphanol. Yohimbine can be used as an antidote to rapidly reverse the effects.