Timeline of antibiotics

This is the timeline of antimicrobial (anti-infective) therapy. The years show when a given drug was released onto the pharmaceutical market. This is not a timeline of the development of the antibiotics themselves.

• 1911 - Arsphenamine aka Salvarsan
• 1912 - Neosalvarsan
• 1935 - Prontosil (an oral precursor to sulfanilimide), the first sulfonamide
• 1936 - Sulfanilimide
• 1938 - Sulfapyridine (M&B 693)
• 1939 - sulfacetamide
• 1940 - sulfamethizole
• 1942 - benzylpenicillin, the first penicillin
• 1942 - gramicidin S, the first peptide antibiotic
• 1942 - sulfadimidine
• 1943 - sulfamerazine
• 1944 - streptomycin, the first aminoglycoside
• 1947 - sulfadiazine
• 1948 - chlortetracycline, the first tetracycline
• 1949 - chloramphenicol, the first amphenicol
• 1949 - neomycin
• 1950 - oxytetracycline
• 1950 - penicillin G procaine
• 1952 - erythromycin, the first macrolide
• 1954 - benzathine penicillin
• 1955 - spiramycin
• 1955 - tetracycline
• 1955 - thiamphenicol
• 1955 - vancomycin, the first glycopeptide
• 1956 - phenoxymethylpenicillin
• 1958 - colistin, the first polymyxin
• 1958 - demeclocycline
• 1959 - virginiamycin
• 1960 - methicillin
• 1960 - metronidazole, the first nitroimidazole
• 1961 - ampicillin
• 1961 - spectinomycin
• 1961 - sulfamethoxazole
• 1961 - trimethoprim, the first dihydrofolate reductase inhibitor
• 1962 - cloxacillin
• 1962 - fusidic acid
• 1963 - fusafungine
• 1963 - lymecycline
• 1964 - gentamicin
• 1964 - Cefalotin, the first cephalosporin
• 1966 - doxycycline
• 1967 - carbenicillin
• 1967 - rifampicin
• 1967 - Nalidixic acid, the first quinolone
• 1968 - clindamycin, the second lincosamide
• 1970 - cefalexin
• 1971 - cefazolin
• 1971 - pivampicillin
• 1971 - tinidazole
• 1972 - amoxicillin
• 1972 - cefradine
• 1972 - minocycline
• 1972 - pristinamycin
• 1973 - fosfomycin
• 1974 - talampicillin
• 1975 - tobramycin
• 1975 - bacampicillin
• 1975 - ticarcillin
• 1976 - amikacin
• 1977 - azlocillin
• 1977 - cefadroxil
• 1977 - cefamandole
• 1977 - cefoxitin
• 1977 - cefuroxime
• 1977 - mezlocillin
• 1977 - pivmecillinam

From 1978

• 1979 - cefaclor
• 1980 - cefmetazole
• 1980 - cefotaxime
• 1980 - cefsulodin
• 1980 - piperacillin
• 1981 - co-amoxiclav (amoxicillin/clavulanic acid)
• 1981 - cefoperazone
• 1981 - cefotiam
• 1981 - cefsulodin
• 1981 - latamoxef
• 1981 - netilmicin
• 1982 - ceftriaxone
• 1982 - micronomicin
• 1983 - cefmenoxime
• 1983 - ceftazidime
• 1983 - ceftizoxime
• 1983 - norfloxacin
• 1984 - cefonicid
• 1984 - cefotetan
• 1984 - temocillin
• 1985 - cefpiramide
• 1985 - imipenem/cilastatin, the first carbapenem
• 1985 - ofloxacin
• 1986 - mupirocin
• 1986 - aztreonam
• 1986 - cefoperazone/sulbactam
• 1986 - co-ticarclav (ticarcillin/clavulanic acid)
• 1987 - ampicillin/sulbactam
• 1987 - cefixime
• 1987 - roxithromycin
• 1987 - sultamicillin
• 1987 - ciprofloxacin, the first 2nd-gen fluoroquinolone
• 1987 - rifaximin, the first ansamycin
• 1988 - azithromycin
• 1988 - flomoxef
• 1988 - isepamycin
• 1988 - midecamycin
• 1988 - rifapentine
• 1988 - teicoplanin
• 1989 - cefpodoxime
• 1989 - enrofloxacin
• 1989 - lomefloxacin
• 1989 - moxifloxacin
• 1990 - arbekacin
• 1990 - cefozidime
• 1990 - clarithromycin
• 1991 - cefdinir
• 1992 - cefetamet
• 1992 - cefpirome
• 1992 - cefprozil
• 1992 - ceftibuten
• 1992 - fleroxacin
• 1992 - loracarbef
• 1992 - piperacillin/tazobactam
• 1992 - rufloxacin
• 1993 - brodimoprim
• 1993 - dirithromycin
• 1993 - levofloxacin
• 1993 - nadifloxacin
• 1993 - panipenem/betamipron
• 1993 - sparfloxacin
• 1994 - cefepime
• 1999 - quinupristin/dalfopristin
• 2000 - linezolid, the first oxazolidinone
• 2001 - telithromycin, the first ketolide
• 2003 - daptomycin
• 2005 - tigecycline
• 2005 - doripenem
• 2009 - telavancin, the first Lipoglycopeptide
• 2010 - ceftaroline
• 2011 - fidaxomicin
• 2012 - bedaquiline
• 2013 - telavancin
• 2014 - tedizolid
• 2014 - dalbavancin
• 2015 - ceftolozane/tazobactam

See also

• Timeline of medicine and medical technology
• List of antibiotics, grouped by class