Uldazepam

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Uldazepam
Uldazepam.svg
Systematic (IUPAC) name
(2Z)-7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one O-allyloxime
Identifiers
CAS Number 28546-58-9 N
ATC code none
PubChem CID: 34274
ChemSpider 31577 YesY
UNII VAE9C0350C YesY
KEGG D06263 YesY
Synonyms 7-chloro-5-(2-chlorophenyl)-N-prop-2-enoxy-3H-1,4-benzodiazepin-2-amine
Chemical data
Formula C18H15Cl2N3O
Molecular mass 360.24 g/mol
  • Clc3ccccc3C/2=N/CC(=N/c1c\2cc(Cl)cc1)\NOC\C=C
  • InChI=1S/C18H15Cl2N3O/c1-2-9-24-23-17-11-21-18(13-5-3-4-6-15(13)20)14-10-12(19)7-8-16(14)22-17/h2-8,10H,1,9,11H2,(H,22,23) YesY
  • Key:DTMPGSXFUXZBDK-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Uldazepam is a drug which is a benzodiazepine derivative.[1] It has sedative and anxiolytic effects similar to those of other benzodiazepines.[2][3]

Synthesis

Thio thionamide is even more prone to amidine formation than the lactam itself.

Uldazepam synthesis: J. B. Hester, Jr., DE 2005176  (1970); Chem. Abstr., 73: 99,001t (1970).

Rxn of thionamide (2) with O-allyl-hydroxylamine gave the oximino (3) uldazepam.

See also

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Oelschläger H, Ellaithy MM, Volke J. Mechanism of the polarographic reduction of the tranquilizer uldazepam. (German). Archiv der Pharmazie (Weinheim). 1988 Feb;321(2):69-72.
  3. ↑ Itil TM, Akpinar S, Ozkut H, et al.: Clinical and computerized EEG effects of U-31,920 a new anxiolytic. Current Therapeutic Research. 1974; 16: 642-654.

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