1,2-Dichloropropane

1,2-Dichloropropane

Names
IUPAC name 1,2-Dichloropropane
Other names Propylene dichloride
Identifiers
CAS Number	78-87-5 Y
ChEMBL	ChEMBL44641 Y
ChemSpider	6316 Y
Jmol 3D model	Interactive image
KEGG	C19034 N
PubChem	6564
UNII	RRZ023OFWL Y
InChI InChI=1S/C3H6Cl2/c1-3(5)2-4/h3H,2H2,1H3 Y Key: KNKRKFALVUDBJE-UHFFFAOYSA-N Y InChI=1/C3H6Cl2/c1-3(5)2-4/h3H,2H2,1H3 Key: KNKRKFALVUDBJE-UHFFFAOYAR
SMILES ClCC(Cl)C
Properties
Chemical formula	C3H6Cl2
Molar mass	112.98 g·mol−1
Appearance	Colorless liquid
Odor	like chloroform
Density	1.156 g/cm3
Melting point	−100 °C (−148 °F; 173 K)
Boiling point	95 to 96 °C (203 to 205 °F; 368 to 369 K)
Solubility in water	0.26 g/100 mL (at 20 °C)
Vapor pressure	40 mmHg (20°C)
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

1,2-Dichloropropane is an organic compound classified as a chlorocarbon. It is a colorless, flammable liquid with a sweet odor. it is obtained as a byproduct of the production of epichlorohydrin, which is produced on a large scale.

Uses

1,2-Dichloropropane is an intermediate in the production of perchloroethylene and other chlorinated chemicals. It was once used as a soil fumigant, chemical intermediate, as well as an industrial solvent and was found in paint strippers, varnishes, and furniture finish removers but some of these uses have been discontinued.

Carcinogenity

Following several cases of bile duct cancer among Japanese printing firm employees, an investigation by the Japanese Ministry of Health, Labour and Welfare concluded in March 2013 that these cases were likely due to the use of cleaning agents containing 1,2-dichloropropane. Thus, there is reasonable evidence that 1,2-dichloropropane may be a carcinogen.

Data from animal studies show tumor growth in the liver and mammary glands. Further animal studies involving inhalation toxicity data has caused the National Institute for Occupational Safety and Health to classify 1,2-dichloropropane as a carcinogen and IDLH.