2-dehydropantolactone reductase (A-specific)
From Infogalactic: the planetary knowledge core
| 2-dehydropantolactone reductase (A-specific) | |||||||||
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| Identifiers | |||||||||
| EC number | 1.1.1.168 | ||||||||
| CAS number | Template:CAS | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a 2-dehydropantolactone reductase (A-specific) (EC 1.1.1.168) is an enzyme that catalyzes the chemical reaction
- (R)-pantolactone + NADP+
2-dehydropantolactone + NADPH + H+
Thus, the two substrates of this enzyme are (R)-pantolactone and NADP+, whereas its 3 products are 2-dehydropantolactone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-pantolactone:NADP+ oxidoreductase (A-specific). Other names in common use include 2-oxopantoyl lactone reductase, ketopantoyl lactone reductase, 2-ketopantoyl lactone reductase, and 2-dehydropantoyl-lactone reductase (A-specific).
References
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