3-Hydroxypropionate pathway

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3-Hydroxypropionate pathway is a process that allows some bacteria to generate 3-Hydroxypropionate utilizing carbon dioxide. In this pathway CO2 is fixed (i.e. incorporated) by the action of two enzymes, acetyl-CoA carboxylase and propionyl-CoA carboxylase. These enzymes generate malyl-CoA and glyoxylate, respectively. Malyl-CoA is further split into acetyl-CoA to replenish this cycle. This pathway has been demonstrated in Chloroflexus, a nonsulfur photosynthetic bacterium, however other studies suggest that 3-hydroxypropionate pathway is utilized by several chemotrophic archaea.

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