4-Hydroxycyclohexanecarboxylate dehydrogenase

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4-hydroxycyclohexanecarboxylate dehydrogenase
Identifiers
EC number 1.1.1.226
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 4-hydroxycyclohexanecarboxylate dehydrogenase (EC 1.1.1.226) is an enzyme that catalyzes the chemical reaction

trans-4-hydroxycyclohexanecarboxylate + NAD+ \rightleftharpoons 4-oxocyclohexanecarboxylate + NADH + H+

Thus, the two substrates of this enzyme are trans-4-hydroxycyclohexanecarboxylate and NAD+, whereas its 3 products are 4-oxocyclohexanecarboxylate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase. This enzyme is also called trans-4-hydroxycyclohexanecarboxylate dehydrogenase.

References

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