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File:8OHPBZI structure.png
Systematic (IUPAC) name
CAS Number 251327-33-0
ATC code none
PubChem CID: 10353845
ChemSpider 8529297 YesY
Chemical data
Formula C15H21NO
Molecular mass 231.34 g·mol−1

8-OH-PBZI is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D3 receptor.[1][2][3]


  1. Scheideler, MA; Martin, J; Hohlweg, R; Rasmussen, JS; Naerum, L; Ludvigsen, TS; Larsen, PJ; Korsgaard, N; Crider, AM; Ghosh, D; Cruse, SF; Fink-Jensen, A (1997). "The preferential dopamine D3 receptor agonist cis-8-OH-PBZI induces limbic Fos expression in rat brain". European Journal of Pharmacology. 339 (2–3): 261–70. PMID 9473144. doi:10.1016/S0014-2999(97)01372-1. 
  2. Fink-Jensen, A; Nielsen, EB; Hansen, L; Scheideler, MA (1998). "Behavioral and neurochemical effects of the preferential dopamine D3 receptor agonist cis-8-OH-PBZI". European Journal of Pharmacology. 342 (2–3): 153–61. PMID 9548380. doi:10.1016/S0014-2999(97)01494-5. 
  3. Malik, P; Andersen, MB; Peacock, L (2004). "The effects of dopamine D3 agonists and antagonists in a nonhuman primate model of tardive dyskinesia". Pharmacology, Biochemistry, and Behavior. 78 (4): 805–10. PMID 15301939. doi:10.1016/j.pbb.2004.05.019.