Acantholysis
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| Acantholysis | |
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Foot-and-mouth disease - acantholysis in a sample of a skin vesicle: Necrosis of the stratum spinosum can be observed, and keratinocytes floating in the vesicular fluid (spongiosa).
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| Specialty | Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value). |
| ICD-10 | L11.9 (ILDS L11.900) |
| DiseasesDB | 31172 |
| Patient UK | Acantholysis |
Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes,[1] seen in diseases such as pemphigus vulgaris.[2] It is absent in bullous pemphigoid, making it useful for differential diagnosis.
This histological feature is also seen in herpes simplex infections (HSV 1 and 2) and Vericella zoster infections (Chicken pox and Shingles).
See also
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References
- ↑ Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) Robbins & Cotran Pathologic Basis of Disease (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.
- ↑ Medical Dictionary Entry
