Apetala 2
| AP2 domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Structure of the GCC-box binding domain in complex with DNA.[1]
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| Identifiers | |||||||||
| Symbol | AP2 | ||||||||
| Pfam | PF00847 | ||||||||
| Pfam clan | CL0081 | ||||||||
| InterPro | IPR001471 | ||||||||
| SMART | SM00380 | ||||||||
| PROSITE | PS51032 | ||||||||
| SCOP | 3gcc | ||||||||
| SUPERFAMILY | 3gcc | ||||||||
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| Apetala 2 | |
|---|---|
| Identifiers | |
| Symbol | AP2 |
| Entrez | 829845 |
| UniProt | P47927 |
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Apetala 2 (AP2) is a gene coding for a member of a large family of transcription factors, the AP2/EREBP family. In Arabidopsis thaliana which plays a role in the ABC model of flower development.[2] It was originally thought that this family of proteins was plant-specific, however recent studies have shown that apicomplexans, including the causative agent of malaria, Plasmodium falciparum encode a related set of transcription factors, called the ApiAP2 family.[3]
In the A. thaliana transcription factor RAV1 the N-terminal AP2 domain binds 5'-CAACA-3' sequence, while the C-terminal highly conserved B3 domain binds 5'-CACCTG-3' sequence.[4]
References
External links
- APETALA2 protein, Arabidopsis at the US National Library of Medicine Medical Subject Headings (MeSH)
- AP2 family, ERF family , RAV family At PlantTFDB: Plant Transcription Factor Database
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