Azapropazone

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Azapropazone
Azapropazone.svg
Azapropazone molecule
Systematic (IUPAC) name
(RS)-5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione
Clinical data
Trade names Rheumox
AHFS/Drugs.com International Drug Names
Legal status
  • UK: POM (Prescription only)
Pharmacokinetic data
Biological half-life 20 hours
Identifiers
CAS Number 13539-59-8 N
ATC code M01AX04 (WHO)
PubChem CID: 26098
ChemSpider 24310 YesY
UNII K2VOT966ZI YesY
KEGG D02966 YesY
ChEBI CHEBI:38010 YesY
ChEMBL CHEMBL1231131 N
Chemical data
Formula C16H20N4O2
Molecular mass 300.36 g/mol
  • O=C3N/1N(c2c(\N=C\1N(C)C)ccc(c2)C)C(=O)C3CCC
  • InChI=1S/C16H20N4O2/c1-5-6-11-14(21)19-13-9-10(2)7-8-12(13)17-16(18(3)4)20(19)15(11)22/h7-9,11H,5-6H2,1-4H3 YesY
  • Key:MPHPHYZQRGLTBO-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Azapropazone is a non-steroidal anti-inflammatory drug. It is manufactured by Goldshield under the tradename Rheumox.[1]

It was available in the UK as a prescription-only drug, with restrictions due to certain contra-indications and side-effects.[2] Azopropazone has now been discontinued in the British National Formulary.

Azapropazone has a half-life of approximately 20 hours in humans and is not extensively metabolized.[3]

References

  1. http://home.intekom.com/pharm/cont_eth/rheumox.html
  2. http://www.patient.co.uk/showdoc/30002267/
  3. Lua error in package.lua at line 80: module 'strict' not found.



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