BCAM
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Basal cell adhesion molecule is a protein that in humans is encoded by the BCAM gene.[1] BCAM has also recently been designated CD239 (cluster of differentiation 239).
Function
Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene.[1]
Interactions
BCAM has been shown to interact with Laminin, alpha 5.[2][3]
References
Further reading
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External links
- BCAM protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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