Baeyer–Drewson indigo synthesis

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The Baeyer–Drewson indigo synthesis (1882) is an organic reaction in which indigo is prepared from 2-nitrobenzaldehyde and acetone [1][2]

The reaction is classified as an aldol condensation. As a practical route to indigo, this method was displaced by routes from aniline.[3]

Mechanism

Note

In the English literature this reaction is usually called Baeyer–Drewson reaction, although the author of the original paper was called Drewsen.

References

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  3. Elmar Steingruber "Indigo and Indigo Colorants" Ullmann's Encyclopedia of Industrial Chemistry 2004, Wiley-VCH, Weinheim. doi: 10.1002/14356007.a14_149.pub2

External links