Besonprodil

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Besonprodil
Besonprodil structure.png
Systematic (IUPAC) name
6-[2-(4-[(4-fluorophenyl)methyl]piperidin-1-yl)ethylsulfinyl]-3H-1,3-benzoxazol-2-one
Identifiers
CAS Number 253450-09-8 N
ATC code none
PubChem CID: 156328
ChemSpider 137662 YesY
UNII 5K3N2D15WW YesY
ChEMBL CHEMBL219631 YesY
Synonyms Besonprodil, CI-1041
Chemical data
Formula C21H23FN2O3S
Molecular mass 402.481 g/mol
  • c4cc(F)ccc4CC(CC2)CCN2CCS(=O)c(cc1o3)ccc1nc3=O
  • InChI=1S/C21H23FN2O3S/c22-17-3-1-15(2-4-17)13-16-7-9-24(10-8-16)11-12-28(26)18-5-6-19-20(14-18)27-21(25)23-19/h1-6,14,16H,7-13H2,(H,23,25) YesY
  • Key:FCBQJNCAKZSIAH-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Besonprodil (CI-1041) is a drug which acts as an NMDA antagonist, selective for the NR2B subunit.[1][2] It is under development as a supplemental medication for Parkinson's disease, and has been shown in animals to be effective in counteracting the dyskinesias associated with long term treatment with levodopa and related drugs.[3][4][5][6][7]

References

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