Blaise ketone synthesis
From Infogalactic: the planetary knowledge core
The Blaise ketone synthesis (named after Edmond E. Blaise) is the chemical reaction of acid chlorides with organozinc compounds to give ketones.[1] [2]
The reaction also works with organocuprates.[3][4]
Reviews have been written.[5] [6]
Variations
Blaise-Maire reaction
The Blaise-Maire reaction is the Blaise ketone synthesis using β-hydroxy acid chlorides to give β-hydroxyketones, which are converted into α,β-unsaturated ketones using sulfuric acid.[7]
See also
References
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