Buclizine
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Systematic (IUPAC) name | |
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(RS)-1-[(4-chlorophenyl)- phenyl-methyl]-4- [(4-tert-butylphenyl) methyl] piperazine
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Clinical data | |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
Identifiers | |
CAS Number | 82-95-1 ![]() |
ATC code | R06AE01 (WHO) |
PubChem | CID: 6729 |
IUPHAR/BPS | 7134 |
DrugBank | DB00354 ![]() |
ChemSpider | 6473 ![]() |
UNII | 0C94V6X681 ![]() |
ChEBI | CHEBI:3205 ![]() |
ChEMBL | CHEMBL1201271 ![]() |
Chemical data | |
Formula | C28H33ClN2 |
Molecular mass | 433.028 g/mol |
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Buclizine is an antihistamine and anticholinergic of the piperazine derivative family. It is considered to be an antiemetic, similar to meclizine.[1]
In the United Kingdom, buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare at migraine sufferers.[2]
References
Aminoalkyl ethers |
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Substituted alkylamines | |||||||||
Substituted ethylenediamines |
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Phenothiazine derivatives | |||||||||
Piperazine derivatives | |||||||||
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Others |
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Simple piperazines (no additional rings) |
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Phenylpiperazines |
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Benzylpiperazines | |
Diphenylalkylpiperazines (benzhydrylalkylpiperazines) |
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Pyrimidinylpiperazines | |
Pyridinylpiperazines | |
Benzo(iso)thiazolylpiperazines | |
Tricyclics (piperazine attached via side chain) |
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Others/Uncategorized |
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