Budipine
From Infogalactic: the planetary knowledge core
Systematic (IUPAC) name | |
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1-tert-butyl-4,4-diphenylpiperidine[1]
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Clinical data | |
AHFS/Drugs.com | International Drug Names |
Identifiers | |
CAS Number | 57982-78-2 |
ATC code | N04BX03 (WHO) |
PubChem | CID: 68778 |
ChemSpider | 62021 |
UNII | L9026OPI2Z |
KEGG | D07306 |
ChEMBL | CHEMBL334491 |
Chemical data | |
Formula | C21H27N |
Molecular mass | 293.446 g/mol |
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Budipine (brand name Parkinsan) is an antiparkinson agent marketed for the treatment of Parkinson's disease.[2][3][1]
While its exact mechanism of action is not well characterized,[2] it is believed to be an NMDA receptor antagonist,[4][5] but also promoting the synthesis of dopamine.[6]
Because it provides additional benefits relative to existing treatments, it probably does not precisely mimic the mechanism of an existing known treatment.[6][7]
See also
- AD-1211
- Delucemine
- Diphenidine
- Ephenidine
- Fluorolintane
- Lanicemine
- Methoxphenidine (MXP)
- MT-45
- Remacemide
References
- ↑ Martndale: The Complete Drug Reference, 35th Ed.
- ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ J. Kornhuber, B. Herr, J. Thome, P. Riederer. "The antiparkinsonian drug budipine binds to NMDA and sigma receptors in postmortem human brain tissue". J.Neural Transm.Suppl. 46:127-133, 1995. PMID 8821048
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