CACNG4

Calcium channel, voltage-dependent, gamma subunit 4
Identifiers
Symbols	CACNG4 ; MGC11138; MGC24983
External IDs	OMIM: 606404 MGI: 1859167 HomoloGene: 8674 GeneCards: CACNG4 Gene
Gene ontology Molecular function • voltage-gated calcium channel activity • channel regulator activity Cellular component • plasma membrane • integral component of plasma membrane • voltage-gated calcium channel complex • endocytic vesicle membrane • AMPA glutamate receptor complex Biological process • transport • synaptic transmission • transmission of nerve impulse • membrane depolarization • calcium ion transmembrane transport • regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27092	54377
Ensembl	ENSG00000075461	ENSMUSG00000020723
UniProt	Q9UBN1	Q9JJV4
RefSeq (mRNA)	NM_014405	NM_019431
RefSeq (protein)	NP_055220	NP_062304
Location (UCSC)	Chr 17: 66.96 – 67.03 Mb	Chr 11: 107.73 – 107.79 Mb
PubMed search	[1]	[2]

Voltage-dependent calcium channel gamma-4 subunit is a protein that in humans is encoded by the CACNG4 gene.

L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes.

See also

• Voltage-dependent calcium channel

External links

• CACNG4 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.