CD3D

CD3d molecule, delta (CD3-TCR complex)
250px PDB rendering based on 1xiw.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1XIW
Identifiers
Symbols	CD3D ; CD3-DELTA; IMD19; T3D
External IDs	OMIM: 186790 MGI: 88331 HomoloGene: 585 GeneCards: CD3D Gene
Gene ontology Molecular function • transcription coactivator activity • transmembrane signaling receptor activity • protein heterodimerization activity Cellular component • cytoplasm • plasma membrane • integral component of membrane • T cell receptor complex • alpha-beta T cell receptor complex Biological process • cell surface receptor signaling pathway • T cell differentiation • T cell costimulation • positive thymic T cell selection • positive regulation of transcription from RNA polymerase II promoter • regulation of immune response • T cell receptor signaling pathway Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE CD3D 213539 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	915	12500
Ensembl	ENSG00000167286	ENSMUSG00000032094
UniProt	P04234	P04235
RefSeq (mRNA)	NM_000732	NM_013487
RefSeq (protein)	NP_000723	NP_038515
Location (UCSC)	Chr 11: 118.34 – 118.34 Mb	Chr 9: 44.98 – 44.99 Mb
PubMed search	[1]	[2]

T-cell surface glycoprotein CD3 delta chain is a protein that in humans is encoded by the CD3D gene.

Interactions

CD3D has been shown to interact with CD8A.

See also

• CD3 (immunology)
• Cluster of differentiation

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.