CGP-35348

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CGP-35348
CGP-35348.svg
Systematic (IUPAC) name
3-aminopropyl(diethoxymethyl)phosphinic acid
Identifiers
CAS Number 123690-79-9 YesY
PubChem CID: 107699
IUPHAR/BPS 1069
ChemSpider 96869 N
Chemical data
Formula C8H20NO4P
Molecular mass 225.222 g/mol
  • CCOC(OCC)P(=O)(CCCN)O
  • InChI=1S/C8H20NO4P/c1-3-12-8(13-4-2)14(10,11)7-5-6-9/h8H,3-7,9H2,1-2H3,(H,10,11) N
  • Key:QIIVUOWTHWIXFO-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

CGP-35348 is a compound used in scientific research which acts as an antagonist at GABAB receptors.[1][2][3]

CGP-35348 was ineffective up to 100 μM to antagonice the inhibitory release of GABA elicited by baclofen, doing it selective as GABAB heteroreceptor antagonist. [4] Moreover, CGP35348 was about threefold less potent to antagonize GHB and GBL than baclofen and SKF97541. [5]

References

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  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.


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