Cheryll Tickle

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Cheryll Tickle
Born Cheryll Anne Tickle
(1945-01-18) January 18, 1945 (age 79)[1]
Fields Developmental biology
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Thesis Quantitative studies on the positioning of cells in aggregates (1970)
Influenced Jeremy Farrar[2][3]
Notable awards <templatestyles src="Plainlist/styles.css"/>
Website
www.bath.ac.uk/bio-sci/contacts/academics/cheryll_tickle

Cheryll Anne Tickle, CBE FRS[4] FRSE FMedSci, is a distinguished British scientist, known for her work in developmental biology and specifically for her research into the process by which vertebrate limbs develop ab ovo. She is an Emeritus Professor at the University of Bath.[6][7]

Education

Tickle was educated at the University of Cambridge graduating with a Master of Arts degree in 1967, and received her Ph.D. from the University of Glasgow in 1970.[8][9]

Career

She worked as a postdoctoral researcher at Yale University, as a lecturer and reader at the Middlesex Hospital Medical School, and (after Middlesex merged with it in 1987) a reader and professor at University College London. She then moved to the University of Dundee in 1998, where she became Foulerton Professor of the Royal Society in 2000, and moved again to the University of Bath in 2007, retaining the Foulerton Professor title.[10][11]

Research

Tickle's research in Developmental Biology investigates how single cells, the fertilised egg, gives rise to a new individual during embryogenesis.[12][13][14][15][16][17][18][19][20][21][22][23][24][25]

Awards and honours

Tickle was elected as a fellow of the Royal Society in 1998, a fellow of the Royal Society of Edinburgh in 2000, a fellow of the Academy of Medical Sciences in 2001, and a member of the European Molecular Biology Organisation in 2001. In 2004 the University of St. Andrews awarded her an honorary doctorate. In 2005 she was named a Commander of The Most Excellent Order of the British Empire (CBE).[26] She also serves as a governor of the Caledonian Research Foundation.[27] Her nomination for the Royal Society reads: <templatestyles src="Template:Blockquote/styles.css" />

Distinguished for her contribution to developmental biology. She demonstrated a quantitative relationship between the signal from the polarizing region in the embryo limb and the pattern digits, and that a similar signal was present in mammals. She discovered that local application of retinoic acid can mimic the signal from the polarizing region. Both these signals were shown to control homeobox gene expression. She has now shown that the signal from the apical ridge which is essential for limb development is a fibroblast growth factor. Her work is characterized by outstanding experimental skill, design and interpretation.[4]

Personal life

Tickle married John Gray in 1979.[1]

References

  1. 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.(subscription required)
  2. Jeremy Farrar intervied on the Life Scientific by Jim Al-Khalili, BBC Radio 4 2014-07-15
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  5. Professor Cheryll Tickle FRS FRSE FMedSci
  6. List of publications from Microsoft Academic Search
  7. Cheryll Tickle's publications indexed by the Scopus bibliographic database, a service provided by Elsevier.
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  10. Speaker profile, CDB Symposium 2005, Center for Developmental Biology, Japan.
  11. Faculty profile, Department of Biology and Biochemistry, Univ. of Bath.[dead link]
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  26. Honours and awards, College of Life Sciences, Univ. of Dundee.[dead link]
  27. About the Caledonian Research Foundation.[dead link]