A chronic condition is a human health condition or disease that is persistent or otherwise long-lasting in its effects or a disease that comes with time. The term chronic is usually applied when the course of the disease lasts for more than three months. Common chronic diseases include arthritis, asthma, cancer, COPD, diabetes and viral diseases such as hepatitis C and HIV/AIDS.
The non-communicable diseases are also usually lasting medical conditions but are separated by their non-infectious causes. In contrast, some chronic diseases, such as HIV/AIDS, are caused by transmissible infections.
Chronic diseases constitute a major cause of mortality and the World Health Organization (WHO) reports chronic non-communicable conditions to be by far the leading cause of mortality in the world, representing 35 million deaths in 2005 and over 60% of all deaths.
Examples of chronic diseases and health conditions include:
- Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases
- Autoimmune diseases, such as ulcerative colitis, lupus erythematosus, Crohn's Disease, Coeliac Disease, Hashimoto's Thyroiditis and Relapsing polychondritis
- Cancer / neoplastic diseases not amenable to be cured
- Cardiovascular diseases: cerebrovascular disease, heart failure, ischemic cardiopathy
- Myalgic encephalomyelitis
- Chronic graft-versus-host disease (GVHD)
- Chronic hepatitis
- Cerebral palsy (all types)
- Chronic pain syndromes, such as post-vasectomy pain syndrome and complex regional pain syndrome
- Chronic osteoarticular diseases: osteoarthritis, rheumatoid arthritis
- Chronic renal failure, Chronic Kidney Disease
- Chronic respiratory diseases: asthma, chronic obstructive pulmonary disease (COPD), pulmonary hypertension
- Deafness and hearing impairment
- Diabetes mellitus
- Mental illness
- Periodontal disease
- Sickle Cell Anemia and other hemoglobin disorders
- Thyroid disease
- Transplant recipients on immunosuppressants
- Lyme Disease
- Blood Pressure abnormalities
- Ehlers-Danlos Syndrome (Various types)
- Sleep apnea
- Postural Orthostatic Tachycardia Syndrome
- Multiple Sclerosis
While risk vary with age and gender, most of the common chronic diseases in the US are caused by dietary, lifestyle and metabolic risk factors that are also responsible for the resulting mortality. Therefore, these conditions might be prevented by behavioral changes, such as quitting smoking, adopting a healthy diet, and increasing physical activity. Social determinants are important risk factors for chronic diseases. Social factors, e.g., socioeconomic status, education level, and race/ethnicity, are a major cause for the disparities observed in the care of chronic disease. Lack of access and delay in receiving care result in worse outcomes for patients from minorities and underserved populations. Those barriers to medical care complicate patients monitoring and continuity in treatment.
In the US, Minorities and low-income populations are less likely to access and receive preventive services necessary to detect conditions at an early stage. In addition, overuse of antibiotic has recently been shown has been associated with chronic disease, for example, chronic liver diseases.
A growing body of evidence supports that prevention is effective in reducing the effect of chronic conditions; in particular, early detection results in less severe outcomes. Clinical preventive services include screening for the existence of the disease or predisposition to its development, counseling and immunizations against infectious agents. Despite their effectiveness, the utilization of preventive services is typically lower than for regular medical services. In contrast to their apparent cost in time and money, the benefits of preventive services are not directly perceived by patient because their effects are on the long term or might be greater for society as a whole than at the individual level.
Therefore, public health programs are important in educating the public, and promoting healthy lifestyles and awareness about chronic diseases. While those programs can benefit from funding at different levels (state, federal, private) their implementation is mostly in charge of local agencies and community-based organizations
Studies have shown that public health programs are effective in reducing mortality rates associated to cardiovascular disease, diabetes and cancer, but the results are somewhat heterogeneous depending on the type of condition and the type of programs involved. For example, results from different approaches in cancer prevention and screening depended highly on the type of cancer. The rising number of patient with chronic diseases has renewed the interest in prevention and its potential role in helping control costs. A report from the Trust for America’s Health suggests that investing $10 per person annually in community-based programs of proven effectiveness and promoting healthy lifestyle (increase in physical activity, healthier diet and preventing tobacco use) could save more than $16 billion annually within 5 years .
In the European Union approximately 70% to 80% of health care budgets across the EU are spent on treating chronic diseases. There is a wealth of knowledge within EU Member States on effective and efficient ways to prevent and manage cardiovascular disease, stroke and type-2 diabetes. There is great potential to reduce the burden of chronic disease by making better use of this knowledge. JA-CHRODIS, a European collaboration across member states, has been designed to exploit this potential through identifying, validating, exchanging and disseminating good practice on chronic diseases.
In the United States, nearly one in two Americans (133 million) has at least one chronic medical condition, with most subjects (58%) between the ages of 18 and 64. The number is projected to increase by more than one percent per year by 2030, resulting in an estimated chronically ill population of 171 million. The most common chronic conditions are high blood pressure, arthritis, respiratory diseases like emphysema, and high cholesterol.
According to research by the Centers for Disease Control and Prevention, chronic disease is also especially a concern in the elderly population in America. Chronic diseases like stroke, heart disease, and cancer were among the leading causes of death among Americans aged 65 or older in 2002, accounting for 61% of all deaths among this subset of the population. While the majority of chronic conditions are found in individuals between the ages of 18 and 64, it is estimated that at least 80% of older Americans are currently living with some form of a chronic condition, with 50% of this population having two or more chronic conditions. The two most common chronic conditions in the elderly are high blood pressure and arthritis, with diabetes, coronary heart disease, and cancer also being reported among the elder population.
In examining the statistics of chronic disease among the living elderly, it is also important to make note of the statistics pertaining to fatalities as a result of chronic disease. Heart disease is the leading cause of death from chronic disease for adults older than 65, followed by cancer, stroke, diabetes, chronic lower respiratory diseases, influenza and pneumonia, and, finally, Alzheimer’s disease. Though the rates of chronic disease differ by race for those living with chronic illness, it is interesting to note that the statistics for leading causes of death among elderly are nearly identical across racial/ethnic groups.
Chronic illnesses cause about 70% of deaths in the US and in 2002 chronic conditions (heart disease, cancers, stroke, chronic respiratory diseases, diabetes, Alzheimer’s disease, mental illness and kidney diseases) were 6 of the top ten causes of mortality in the general US population. In the United States, 90% of seniors have at least one chronic disease, and 77% have two or more chronic conditions.
Chronic diseases are a major factor in the continuous growth of medical care spending. Healthy People 2010 reported that more than 75% of the $2 trillion spent annually in US medical care are due to chronic conditions; spending are even higher in proportion for Medicare beneficiaries (aged 65 years and older). Spending growth is driven in part by the greater prevalence of chronic illnesses, and the longer life expectancy of the population. Also improvement in treatments has significantly extended the life spans of patients with chronic diseases but results in additional costs over long period of time. A striking success is the development of combined antiviral therapies that led to remarkable improvement in survival rates and quality of life of HIV-infected patients.
In addition to direct costs in health care, chronic diseases are a significant burden to the economy, through limitations in daily activities, loss in productivity and loss of days of work. A particular concern is the rising rates of overweight and obesity in all segments of the US population. Obesity itself is a medical condition and not a disease, but it constitutes a major risk factor for developing chronic illnesses, such as diabetes, stroke, cardiovascular disease and cancers. Obesity results in significant health care spending and indirect costs, as illustrated by a recent study from the Texas comptroller reporting that obesity alone cost Texas businesses an extra $9.5 billion in 2009, including more than $4 billion for health care, $5 billion for lost productivity and absenteeism, and $321 million for disability.
- Acute on chronic
- Chronic disease in China
- Chronic disease in Northern Ontario
- Chronic Illness (journal)
- Chronic pain
- Course (medicine)
- Disease management (health)
- Dynamic treatment regimes
- Medical tattoo
- Multiple morbidities
- Natural history of disease
- Virtual Wards (a UK term)
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- Bone Marrow Transplantation journal
- Center for Managing Chronic Disease, University of Michigan
- CHRODIS: EU Joint Action on Chronic Diseases and Promoting Healthy Ageing Across the Life-Cycle
- MEDICC Review theme issue on Confronting Chronic Diseases With longer life expectancies in most countries and the globalization of "Western" diets and sedentarism, the main burden of disease and death from these conditions is falling on already-disadvantaged developing countries and poor communities everywhere.
- Public Health Agency of Canada: Chronic Disease
- World Health Organization: Chronic Disease and Health Promotion