Chrysin

Chrysin

Names
IUPAC name 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one
Other names 5,7-Dihydroxyflavone; NP-005901; Galangin flavanone
Identifiers
CAS Number	480-40-0 Y
ChEBI	CHEBI:75095 N
ChEMBL	ChEMBL117 Y
ChemSpider	4444926 Y
Jmol 3D model	Interactive image
KEGG	C10028 Y
PubChem	5281607
UNII	3CN01F5ZJ5 Y
InChI InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H Y Key: RTIXKCRFFJGDFG-UHFFFAOYSA-N Y InChI=1/C15H10O4/c16-10-6-11(17)15-12(18)8-13 (19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H Key: RTIXKCRFFJGDFG-UHFFFAOYAO
SMILES O=C\1c3c(O/C(=C/1)c2ccccc2)cc(O)cc3O
Properties
Chemical formula	C15H10O4
Molar mass	254.24 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Chrysin is a naturally occurring flavone, a type of flavonoid. It is found in the passion flowers Passiflora caerulea and Passiflora incarnata, and in Oroxylum indicum. It is also found in chamomile, in the mushroom Pleurotus ostreatus, and in honeycomb.

Aromatase inhibition

Studies performed in vivo show that orally administered chrysin does not have clinical activity as an aromatase inhibitor.

Chrysin is available as a bodybuilding supplement and it is taken with the hope of raising testosterone levels or stimulating testosterone production; however, there is no clinical evidence for this effect, as studies show that chrysin has no effect on testosterone levels in men.

Inflammation

Chrysin is under laboratory research for its potential effects on inflammation, but there is no evidence it has anti-inflammatory activity in humans.

Bioavailability

Following oral intake by humans, chrysin has low bioavailability and rapid excretion.