Cianopramine

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Cianopramine
Cianopramine V.1.svg
Systematic (IUPAC) name
5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepine-3-carbonitrile
Identifiers
CAS Number 66834-24-0
ATC code none
PubChem CID: 48126
ChemSpider 43782
UNII 02MNR4P2PM YesY
ChEMBL CHEMBL2106504
Chemical data
Formula C20H23N3
Molecular mass 305.417 g/mol
  • N#Cc1ccc3c(c1)N(c2ccccc2CC3)CCCN(C)C

Cianopramine (INN) (developmental code name Ro 11-2465), also known as 3-cyanoimipramine, is a tricyclic antidepressant related to imipramine that acts as a serotonin reuptake inhibitor[1] and weak serotonin receptor antagonist.[2][3] It was investigated for the treatment of depression but was never marketed.[3]

See also

References

  1. ↑ Kenny M, Lenehan TJ, Lambe R, Darragh A, Brick I, Omer LM. Effects of a single oral dose of 3-cyano-imipramine on serotonin uptake and content of platelets in healthy volunteers. Psychopharmacology (Berlin). 1983;79(4):304-7. PMID 6407042
  2. ↑ Pawłowski L, Kwiatek H, Górka Z. Is Ro 11-2465 (cyan-imipramine) an antagonist of postsynaptic serotonin receptors? Journal of Neural Transmission. 1981;52(1-2):61-72. PMID 7288439
  3. ↑ 3.0 3.1 Lua error in package.lua at line 80: module 'strict' not found.



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