Cirazoline

Cirazoline

Names
IUPAC name 2-[(2-cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole
Identifiers
CAS Number	59939-16-1 Y
ChEMBL	ChEMBL13852 Y
ChemSpider	2663 Y
IUPHAR/BPS	515
Jmol 3D model	Interactive image
MeSH	Cirazoline
PubChem	2765
UNII	QK318GVY3Y Y
InChI InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15) Y Key: YAORIDZYZDUZCM-UHFFFAOYSA-N Y InChI=1/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15) Key: YAORIDZYZDUZCM-UHFFFAOYAV
SMILES O(c1c(cccc1)C2CC2)CC/3=N/CCN\3
Properties
Chemical formula	C13H16N2O
Molar mass	216.279 g/mol
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Cirazoline is a full agonist at the α_1A adrenergic receptor, a partial agonist at both the α_1B and α_1D adrenergic receptors, and a nonselective antagonist to the α₂ adrenergic receptor. It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent.

Cirazoline has also been shown to decrease food intake in rats, purportedly through activation of α₁ adrenoceptors in the paraventricular nucleus in the hypothalamus of the brain.