Cloxestradiol

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Cloxestradiol
Cloxestradiol.svg
Systematic (IUPAC) name
(8R,9S,13S,14S,17S)-13-Methyl-17-(2,2,2-trichloro-1-hydroxyethoxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-ol
Identifiers
CAS Number 54063-33-1
PubChem CID: 194705
ChemSpider 168924
Synonyms 17-(1-Hydroxy-2,2,2-trichloroethoxy)estra-1,3,5(10-trien-3-ol
Chemical data
Formula C20H25Cl3O3
Molecular mass 419.7697 g/mol
  • C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CC[C@@H]2OC(C(Cl)(Cl)Cl)O)O
  • InChI=1S/C20H25Cl3O3/c1-19-9-8-14-13-5-3-12(24)10-11(13)2-4-15(14)16(19)6-7-17(19)26-18(25)20(21,22)23/h3,5,10,14-18,24-25H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18?,19+/m1/s1
  • Key:JVLHMVXGPLKLFV-AJUWMHLFSA-N

Cloxestradiol (INN) is a synthetic, steroidal estrogen that was never marketed.[1] It is an analogue of estradiol with a 2,2,2-trichloroethoxy substitution.[1]

The O,O-diacetate derivative, cloxestradiol acetate (brand name Genovul), has been marketed as an estrogen.[1]

See also

References

  1. 1.0 1.1 1.2 Lua error in package.lua at line 80: module 'strict' not found.



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