Clumping factor A

From Infogalactic: the planetary knowledge core
Jump to: navigation, search

Clumping factor A, or ClfA, is a virulence factor from Staphylococcus aureus (S. aureus) that binds to fibrinogen.

ClfA also has been shown to bind to complement regulator I protein.[1]

It is responsible for the clumping of blood plasma observed when adding S. aureus to human plasma. Clumping factor can be detected by the slide test.

See also


  1. Hair PS, Ward MD, Semmes OJ, Foster TJ, Cunnion KM (July 2008). "Staphylococcus aureus clumping factor A binds to complement regulator factor I and increases factor I cleavage of C3b". The Journal of Infectious Diseases. 198 (1): 125–33. PMID 18544012. doi:10.1086/588825.