Codeine-6-glucuronide
From Infogalactic: the planetary knowledge core
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Names | |
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IUPAC name
(5α,6α)-3-methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-yl β-D-glucopyranosiduronic acid
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Identifiers | |
ChemSpider | 4590054 |
Jmol 3D model | Interactive image |
PubChem | 5489029 |
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Properties | |
C24H29NO9 | |
Molar mass | 475.49 g·mol−1 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Codeine-6-glucuronide (C6G) is a major active metabolite of codeine and may be responsible for as much as 60% of the analgesic effects of codeine. C6G exhibits decreased immunosuppressive effects compared to codeine.[1] During its metabolism, codeine is conjugated with glucuronic acid by the enzyme UDP-Glucuronosyltransferase-2B7 (UGT2B7) to form codeine-6-glucuronide.[2][3]
See also
References
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- Glucuronides
- Opioid metabolites
- Morphinans
- Phenols
- Mu-opioid agonists