Compound analgesic
Compound analgesics are those with multiple active ingredients; they include many of the stronger prescription analgesics.
Active ingredients that have been commonly used in compound analgesics include:
- aspirin or ibuprofen
- caffeine
- codeine or oxycodone
- paracetamol (acetaminophen)
- phenacetin
Several such formulations have disappeared from over-the-counter status in drug store aisles and other retail outlets. One example is APC (aspirin, phenacetin, and caffeine) compound tablets common from the 1940s to 1983; because of harmful side effects of phenacetin, Anacin in the U.S. was reformulated to eliminate it; Vincent's APC and Bex,[lower-alpha 1] an Australian cultural icon, are no longer sold. Some others have been judged to contribute too often to substance abuse.[citation needed]
The United States Food and Drug Administration also now requires that manufacturers of compound analgesics unequivocally state each ingredient's purpose.[citation needed]
Footnotes
References
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External links
- APC definition and brief history.
- Bex packaging history at the Powerhouse Museum website.
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