Pure red cell aplasia

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Pure red cell aplasia
Classification and external resources
Specialty Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value).
ICD-10 D60
ICD-9-CM 284.8
DiseasesDB 29063
eMedicine med/1967
Patient UK Pure red cell aplasia
MeSH D012010
[[[d:Lua error in Module:Wikidata at line 863: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]]

Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of anemia affecting the precursors to red blood cells but not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. The condition has been first described by Paul Kaznelson in 1922.[1]

Causes

Causes include:

  • Idiopathic. Many cases of PRCA are considered idiopathic in that there is no discernible cause detected.[5]

Treatment

PRCA is considered an autoimmune disease as it will respond to immunosuppressant treatment such as cyclosporine in many patients,[8] though this approach is not without risk.[9]

It has also been shown to respond to treatments with Rituxan and Tacrolimus.

See also

References

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  6. Petrochko C (2009). "FDA Strengthens Warning on Transplant Drug." Medpage Today. 14 August 2009. Accessed on 19 August 2009.
  7. Online 'Mendelian Inheritance in Man' (OMIM) 105650
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External links