Cyclin E2
From Infogalactic: the planetary knowledge core
| cyclin E2 | |
|---|---|
| Identifiers | |
| Symbol | CCNE2 |
| Entrez | 9134 |
| HUGO | 1590 |
| OMIM | 603775 |
| RefSeq | NM_057749 |
| UniProt | O96020 |
| Other data | |
| Locus | Chr. 8 q22.1 |
Cyclin E2 is a protein that in humans is encoded by the CCNE2 gene. It is a G1 cyclin that binds Cdk2 and is inhibited by p27(Kip1) and p21(Cip1).[1] It plays a role in the G1/S portion of the cell cycle and also has putative interactions with proteins CDKN1A, CDKN1B, and CDK3. Aberrant expression can lead to cancer.[1]
