Cyclopiazonic acid
From Infogalactic: the planetary knowledge core
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Names | |
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IUPAC name
(6aR,11aS,11bR)-10-Acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one
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Identifiers | |
18172-33-3 | |
ChEBI | CHEBI:22450 |
ChEMBL | ChEMBL480627 |
ChemSpider | 21106432 |
5350 | |
Jmol 3D model | Interactive image |
PubChem | 65261 |
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Properties | |
C20H20N2O3 | |
Molar mass | 336.39 g·mol−1 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Cyclopiazonic acid (CPA) is a toxic fungal secondary metabolite.[1] Chemically, CPA is related to ergoline alkaloids. CPA was originally isolated from Penicillium cyclopium and subsequently from other fungi including Penicillium griseofulvum, Penicillium camemberti, Penicillium commune, Aspergillus flavus, and Aspergillus versicolor. CPA only appears to be toxic in high concentrations. Biologically, CPA is a specific inhibitor of SERCA ATPase in intracellular Ca2+ storage sites.[2]
References
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