Davis–Beirut reaction
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In chemistry the Davis–Beirut reaction is an annulation reaction first reported by Mark Kurth and Makhluf Haddadin in 2005.[1] It is named after their respective universities; University of California, Davis and American University of Beirut.[2][3]
The reaction originally produced N2-substituted-indazalones, by a reaction between o-nitrosobenzaldehyde and primary amines, under basic conditions.[1] It has subsequently been expanded to produce a variety of 3-hetero-indazoles from a boarder range of starting materials[4][5] under acidic or basic conditions.[6]
References
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