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Skeletal formula of demegestone
Ball-and-stick model of the demegestone molecule
Systematic (IUPAC) name
CAS Number 10116-22-0
ATC code G03DB05 (WHO)
PubChem CID: 93057
ChemSpider 84009
Synonyms RU-2453
Chemical data
Formula C21H28O2
Molecular mass 312.446 g/mol

Demegestone (INN) (brand name Lutionex), also known as 17-methyl-19-norpregna-4,9-diene-3,20-dione, is a 19-norprogesterone derivative and steroidal progestin which was introduced by Roussel in France in 1974.[1][2] Like other 19-norprogesterone derivatives, it has relatively high affinity for the progesterone receptor and shows little or no activity at other steroid hormone receptors.[3]

See also


  1. C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 582–. ISBN 978-0-412-46630-4.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  2. William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 1215–. ISBN 978-0-8155-1856-3.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  3. Ian Milsom (2006). Contraception and Family Planning. Elsevier Health Sciences. pp. 102–. ISBN 0-444-51828-2.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>