Cinchocaine

Cinchocaine

Systematic (IUPAC) name
2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	US: OTC
Routes of administration	topical, intravenous (equine euthanasia)
Identifiers
CAS Number	85-79-0 Y
ATC code	C05AD04 (WHO) D04AB02 N01BB06 S01HA06 S02DA04
PubChem	CID: 3025
IUPHAR/BPS	7159
DrugBank	DB00527 Y
ChemSpider	2917 Y
UNII	L6JW2TJG99 Y
KEGG	D00733 Y
ChEBI	CHEBI:247956 Y
ChEMBL	CHEMBL1086 Y
Chemical data
Formula	C20H29N3O2
Molecular mass	343.463 g/mol
SMILES O=C(c1c2ccccc2nc(OCCCC)c1)NCCN(CC)CC
InChI InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24) Y Key:PUFQVTATUTYEAL-UHFFFAOYSA-N Y
(verify)

Cinchocaine (INN/BAN) or dibucaine (USAN) is an amide local anesthetic. Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia. It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine.

Medical use

Cinchocaine is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle.

Physical properties

Cinchocaine is relatively insoluble in alkaline aquatic solutions.

See also

• Dibucaine number