Dienestrol

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Dienestrol
File:Dienestrol.svg
Systematic (IUPAC) name
4-[4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol; p-[(E,E)-1-Ethylidene-2-(p-hydroxyphenyl)-2-butenyl]phenol
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
Pharmacokinetic data
Protein binding 50 to 80%
Identifiers
CAS Number 84-17-3 N
ATC code G03CB01 (WHO) G03CC02
PubChem CID: 667476
IUPHAR/BPS 7160
DrugBank DB00890 YesY
ChemSpider 580857 YesY
UNII RRW32X4U1F YesY
KEGG D00898 YesY
ChEBI CHEBI:4518 N
ChEMBL CHEMBL1018 YesY
Chemical data
Formula C18H18O2
Molecular mass 266.334 g/mol
  • Oc2ccc(C(/C(c1ccc(O)cc1)=C/C)=C\C)cc2
  • InChI=1S/C18H18O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20H,1-2H3/b17-3+,18-4+ YesY
  • Key:NFDFQCUYFHCNBW-SCGPFSFSSA-N YesY
 NYesY (what is this?)  (verify)

Dienestrol (INN, USAN) (brand names Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol, numerous others), also known as dienoestrol (BAN), is a synthetic, non-steroidal estrogen of the stilbestrol group used to treat menopausal symptoms in the United States and Europe.[1][2][3][4] It was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.[4] Dienestrol is a close analogue of diethylstilbestrol.[5]

Dienestrol diacetate (brand names Faragynol, Gynocyrol, others) also exists and is used medically.[2]

See also

References

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