Difetarsone

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Difetarsone
Skeletal formula of difetarsone
Space-filling model of the difetarsone molecule
Systematic (IUPAC) name
[4-[2-[(4-arsonophenyl)amino]ethylamino]phenyl] arsonic acid
Identifiers
CAS Number 3639-19-8
ATC code P01AR02 (WHO) QP51AD02 (WHO)
PubChem CID: 68199
ChemSpider 61506
UNII G4G9J3Q65W YesY
KEGG D07357
Chemical data
Formula C14H18As2N2O6
Molecular mass 460.146 g/mol

Difetarsone is an antiprotozoal agent. Various studies have shown it to be particularly effective against Trichuris trichiura, commonly known as the whipworm. Prior to the drugs use in the early 1970s, there were few effective treatments for this infection.[1] It has also been used to treat Entamoeba histolytica infections.[2]

Difetarsone often has minor side effects, which include rashes, nausea and vomiting. It has also resulted in angioedema in at least one known case.[2]

References

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