ESAT-6
From Infogalactic: the planetary knowledge core
6 kDa early secretory antigenic target | |
---|---|
Identifiers | |
Symbol | esxA |
Entrez | 886209 |
PDB | 3FAV |
UniProt | P0A564 |
ESAT-6, the 6 kDa early secretory antigenic target produced by Mycobacterium tuberculosis, is a secretory protein and potent T cell antigen.[1] It is used in tuberculosis diagnosis by the whole blood interferon γ test QuantiFERON-TB Gold, in conjunction with CFP-10 and TB7.7.
ESAT-6 has been shown to directly bind to the TLR2 receptor, inhibiting downstream signal transduction.[2]
See also
References
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